Man must not be neglected. personalizing therapies: key to success even in ART

Unfortunately, the man is often neglected in the infertile couple and sometimes we are limited to carrying out a spermiogram.

This happens especially when you decide to perform an ICSI because it is believed that this technique magically overcomes all male problems. Unfortunately, this is not the case in the sense that the introduction of a sperm into the oocyte can lead to fertilization but this is not a guarantee of the quality of the embryo.

Ashraf, head of the Biofertility laboratory, shows how the choice of the right spermatozoon is very important but difficult because it requires great experience, dedicating all the necessary time to this phase. In fact, the content of the DNA found inside the male gamete represents its true quality and the fate of the embryos that form after fertilization can depend precisely on the choice of the right spermatozoa.

Furthermore, carrying out andrological therapy before the ICSI in order to improve the quality of the spermiogram as much as possible can be decisive.

This is especially true when the oocytes are few and are not wasted with an incorrect choice of sperm.

In this sense we can also think about when we have only one oocyte as in the case of ICSI in a natural cycle, i.e. without hormonal stimulation.

Therefore, personalization even in these andrological cases is fundamental and can serve to avoid both egg donation and the use of sperm outside the couple as occurs in embryo donation.

In fact, sometimes one may believe that the spermatozoa from an abnormal spermiogram should not be used.

Yet it is known that even with the spermatozoa taken from the testicle with TESE in the case of azoospermia, excellent pregnancies are achieved.

In fact, even more so in this case, the choice of the right spermatozoa to use can be decisive in establishing the pregnancy.